What is TIPTOP?

The Transforming Intermittent Preventive Treatment for Optimal Pregnancy (TIPTOP) project is an innovative, community-based approach that aims to dramatically increase the number of pregnant women in malaria-affected countries in sub-Saharan Africa receiving antimalarial preventive therapy, thus saving the lives of thousands of mothers and newborns.

This 5-year landmark project will:

Health worker doing research

Generate Evidence

Generate evidence to inform change in policy recommendations across sub-Saharan Africa for the World Health Organization (WHO).


Pregnant mother with toddler

Increase coverage of IPTp

Introduce and set the stage for scale-up of community distribution of intermittent preventive treatment (IPTp) with quality assured (QA) sulfadoxine pyrimethamine (SP).


Hand receiving medication

Increase Demand

Introduce and increase demand for quality-assured (QA) SP.

Malaria in Pregnancy (MiP)

What is the danger of malaria in pregnancy?

Each year MiP is responsible for:

20% of stillbirths in sub-Saharan Africa

100,000 newborn deaths globally

10,000 maternal deaths globally

In malaria-endemic areas, 50 million women will become pregnant each year.

These women are highly susceptible to the consequences of malaria, which lead to:

Increased maternal death

Severe maternal anemia

Low birthweight

Infant death

IPTp-SP works

It provides significant benefit by reducing the incidence of:

Severe maternal anemia: 38%

Low birthweight: 29%

Infant death: 31%

About TIPTOP

An innovative, community-based approach that aims to dramatically increase the number of pregnant women in malaria-affected countries in sub-Saharan Africa receiving life-saving antimalarial treatment.


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